Helper or Culprit: Re-Examining the Role of Fibroblasts in Dilated Cardiomyopathy
September 11, 2025 | Categories: Core Faculty, Research, Uncategorized |In a paper published in Science, a multidisciplinary ISCRM research team of biologists, engineers, and physicians shows that fibroblasts, often thought of as helpers, may weaken the heart by causing a harmful cycle of stiffening and scarring. Read More
How Small Molecules Have a Big Impact on the Heart
October 23, 2024 | Categories: Core Faculty, Research |Researchers at UW and UCSD use a multiscale modeling tool show how small infusions of myosin can have a big impact on the whole heart. Read More
Why Tiny Changes in Protein Structure Can Lead to Big Problems for the Heart
May 2, 2024 | Categories: Research, Uncategorized |An NIH-funded collaboration involving ISCRM researchers has published a study describing how complementary areas of expertise produced new insights about hypertrophic cardiomyopathy at the protein, cell, and tissue levels. Read More
Gene Editing May Help Address Arrhythmia Challenges in Heart Regeneration
June 21, 2021 | Categories: Heart Regeneration, Research, Uncategorized |New data presented by ISCRM Director Chuck Murry suggests gene-editing may be the key to clearing a major hurdle for researchers hoping to remuscularize injured hearts with stem cell-derived cardiomyocytes Read More
ISCRM Researchers Use Rainbow Reporters to Examine Proliferation of Engrafted Heart Cells
April 19, 2021 | Categories: Core Faculty, Heart Regeneration, Research, Uncategorized |ISCRM investigators use rainbow cell technology to demonstrate that injected heart cells proliferate, a finding that could help researchers enhance the efficacy of cell therapy for heart disease and other conditions. Read More
ISCRM Researchers Pursue Personalized Medicine for Heart Failure
December 3, 2020 | Categories: Award, Research |With a Collaborative Science Award from the American Heart Association Jen Davis, Farid Moussavi-Harami , and Tom Daniel are on a mission to develop new tools to help cardiologists personalize treatments for certain heart diseases too. Read More
ISCRM Researchers Discover “Missing Piece” of the Heart Regeneration Puzzle
August 21, 2019 | Categories: Announcements, Research |Nearly 18 million people die each year from heart disease, making it the leading cause of death in the world. In the United States alone, the annual economic impact of heart disease exceeds $200 billion, a figure that is expected to rise dramatically. Read More
Give your heart a break
December 3, 2012 | Categories: Research |UW geneticists have recently come across a discovery that can possibly help alleviate the high prevalence of heart disease, which could have profound implications in the field of medicine. Researchers, […] Read More