Protein-Based Biomaterial Protects Injected Cells, Improves Engraftment

March 13, 2024 | Categories: Core Faculty, Research | Tagged: , , , ,

Research led by Cole DeForest, PhD in collaboration with Chuck Murry, MD, PhD and Kelly Stevens, PhD details a new protein-based biomaterial that could help improve engraftment and function following injectable cell therapies. Read More

Gene-Edits Safely Reduce Irregular Heartbeats in Cell Therapy for Heart Disease

April 6, 2023 | Categories: Core Faculty, Heart Regeneration, Research, Uncategorized | Tagged: ,

Researchers in the Murry Lab have demonstrated that a quadruple gene editing approach safely suppresses irregular heartbeats in stem cell therapy for injured hearts. Read More

Gene Editing May Help Address Arrhythmia Challenges in Heart Regeneration

June 21, 2021 | Categories: Heart Regeneration, Research, Uncategorized | Tagged: , , ,

New data presented by ISCRM Director Chuck Murry suggests gene-editing may be the key to clearing a major hurdle for researchers hoping to remuscularize injured hearts with stem cell-derived cardiomyocytes Read More

Rainbow Heart

ISCRM Researchers Use Rainbow Reporters to Examine Proliferation of Engrafted Heart Cells

April 19, 2021 | Categories: Core Faculty, Heart Regeneration, Research, Uncategorized | Tagged: , , , ,

ISCRM investigators use rainbow cell technology to demonstrate that injected heart cells proliferate, a finding that could help researchers enhance the efficacy of cell therapy for heart disease and other conditions. Read More

ISCRM Researchers Discover “Missing Piece” of the Heart Regeneration Puzzle

August 21, 2019 | Categories: Announcements, Research | Tagged: , , , ,

Nearly 18 million people die each year from heart disease, making it the leading cause of death in the world. In the United States alone, the annual economic impact of heart disease exceeds $200 billion, a figure that is expected to rise dramatically. Read More

ISCRM Labs Collaborate to Grow Heart Tissue In Vitro

February 4, 2019 | Categories: Research | Tagged: , , ,

February 4, 2019 Heart failure is the leading cause of death in the world. In the United States alone, hundreds of thousands of people succumb to the disease every year, […] Read More

Researchers use stem cells to restore heart function in primates

July 2, 2018 | Categories: Research | Tagged: , ,

Results of a study published today in Nature Biotechnology suggest techniques that could treat patients with heart failure. Researchers at UW Medicine in Seattle have successfully used human stem cells to restore heart function in monkeys with heart failure. The findings suggest that the technique will be effective in patients with heart failure, the leading cause of death in the world. Read More

Faculty headshot of Charles Murry, MD, PhD

New Leadership Announced at ISCRM

May 1, 2017 | Categories: Announcements | Tagged:

We have announced the appointment of Professor Charles (Chuck) Murry as the new Director of ISCRM. Murry is the successor to ISCRM’s Founding Director and eminent pharmacologist, Professor Randall T. […] Read More

Pioneering work on stem-cell therapies at UW deserves state support

April 9, 2017 | Categories: Research | Tagged: , , , , ,

IF you have a heart attack, hopefully you’ll survive. But your body will be forever changed. The world’s best doctors can’t undo the damage; instead, drugs and devices will help […] Read More