A colorful, abstract 3D visualization of clustered organic shapes, radiating outward from two central white ovals, resembling a scientific or microscopic model against a black background.

Stevens Lab Reconstructs Human Liver Tissue Cell Architecture in 3D

March 6, 2026 | Categories: Core Faculty, Research | Tagged: , ,

ISCRM faculty member Kelly Stevens is the senior author of a study, published in Science Advances, that unveils 3D reconstructions of human liver tissue offering unprecedented detail at the cellular level. Read More

A small, translucent, 3D-printed plastic object with a rectangular base, two vertical supports, and an oval-shaped top piece, placed on a gray surface.

User-Friendly 3D-Printed Device Will Allow Researchers to Model Human Tissue With Increased Control and Complexity

April 30, 2025 | Categories: Core Faculty, Research, Uncategorized | Tagged: , ,

The device known as STOMP, developed by researchers from the Sniadecki and Theberge Labs, is small enough to fit on a human fingertip and is compatible with existing tissue engineering technology. Read More

Diagram illustrating 3D brain microvessels under different conditions: resting, after 8 hours with TNF, and after 8 and 24 hours with parasites, showing changes like microparticles, gaps, filaments, and ghost cells.

Zheng Lab Unveils Platform for Modeling Cerebral Malaria in 3D

November 20, 2023 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

A new paper from the Zheng Lab, published in Cell Reports, unveils a technique for probing cerebral malaria inflammation in 3D engineered human brain microvessels. Read More

A digital image shows green wolf head patterns inside a circle on the left, and a glowing green silhouette of a dog standing in a 3D grid cube on the right, both on a black background.

SpyLigation Uses Light to Switch on Proteins

April 17, 2023 | Categories: Core Faculty, Research | Tagged: , , ,

Light-activation technology developed by the Cole DeForest Research Group has potential applications in tissue engineering, regenerative medicine, and understanding how the body works. Read More

Cover of Advanced Healthcare Materials featuring a stylized illustration of blood vessels in red and blue with cell nuclei in purple, and diagrams of glomeruli above, showing a process or transformation with arrows.

Engineering Microvasculature in Full 3D Complexity

March 4, 2021 | Categories: Core Faculty, Research | Tagged: , , ,

ISCRM researchers led by Ying Zheng, PhD, detail a method to generate microvaculature in full 3D complexity using multiphoton ablation and laser-guided cellularization Read More

A four-panel figure showing fluorescent microscopy images of microfabricated structures: (a) a 3D bar graph, (b) multiple grid patterns, (c) a horizontal grid, and (d) a tree-like branching pattern, all with scale bars.

DeForest Lab Pioneers 4D Biomimicry Systems With Ingenuity, Collaboration, and an NIH Grant

October 1, 2020 | Categories: Award, Core Faculty, Uncategorized | Tagged: , ,

In reality show terms, Cole DeForest and his team manufacture tiny bio-worlds staged to mimic living systems, force an eclectic cast of cells to cohabitate, apply light, heat, and chemicals to stir up drama, then record it all with sophisticated monitoring equipment. What they see on the tiniest scales, could have major implications for medicine. Read More

Side-by-side images: on the left, a translucent blue object with geometric shapes; on the right, a heat map with bright yellow, orange, and red colors centered within cooler blue and black edges.

Stevens Lab Unveils Novel System for Regulating Gene Expression with Heat

September 30, 2020 | Categories: Research, Uncategorized | Tagged: , , , ,

Researchers hoping to create disease models or regenerate organs need systems that precisely mimic the degree of complexity found in the natural world. The Stevens Lab is helping to answer the call with a new system that regulates gene expression patterns using heat Read More