Gloved hands holding and assembling scientific equipment with transparent chambers and labeled cassette, likely used for laboratory experiments or cell culture work.

$7.3 Million NIH Grant Funds Effort to Advance Kidney Microphysiological Testing Platforms

February 12, 2024 | Categories: Core Faculty, Research | Tagged: , , , , ,

NIH Funding will allow ISCRM faculty members Ed Kelly and Beno Freedman to lead the effort to advance kidney-on-a-chip and organoid testing technology and submit a 3D engineered platform for FDA approval. Read More

Diagram illustrating 3D brain microvessels under different conditions: resting, after 8 hours with TNF, and after 8 and 24 hours with parasites, showing changes like microparticles, gaps, filaments, and ghost cells.

Zheng Lab Unveils Platform for Modeling Cerebral Malaria in 3D

November 20, 2023 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

A new paper from the Zheng Lab, published in Cell Reports, unveils a technique for probing cerebral malaria inflammation in 3D engineered human brain microvessels. Read More

Cover of Advanced Healthcare Materials featuring a stylized illustration of blood vessels in red and blue with cell nuclei in purple, and diagrams of glomeruli above, showing a process or transformation with arrows.

Engineering Microvasculature in Full 3D Complexity

March 4, 2021 | Categories: Core Faculty, Research | Tagged: , , ,

ISCRM researchers led by Ying Zheng, PhD, detail a method to generate microvaculature in full 3D complexity using multiphoton ablation and laser-guided cellularization Read More

A glowing, glittery ring with purple and green specks floats against a black background, forming a smooth, continuous circular shape.

Zheng Lab Uses New 3D Model to Study Effect of Curvature on Endothelial Cells

September 16, 2020 | Categories: Research | Tagged: , , ,

Every day, million of cars navigate a complex network of wide, straight highways, busy streets and avenues, and side roads that bend and curve in unpredictable patterns. Now a new 3D modeling tool will help scientists study even more complex traffic patterns at work in our blood vessels. Read More

Fluorescent microscopic image showing a grid pattern outlined in bright pink, with green and blue speckles in the background. The grid is composed of nine squares, and a white scale bar appears in the lower right corner.

ISCRM Labs Collaborate to Grow Heart Tissue In Vitro

February 4, 2019 | Categories: Research | Tagged: , , ,

February 4, 2019 Heart failure is the leading cause of death in the world. In the United States alone, hundreds of thousands of people succumb to the disease every year, […] Read More