News

Side-by-side images: on the left, a translucent blue object with geometric shapes; on the right, a heat map with bright yellow, orange, and red colors centered within cooler blue and black edges.

Stevens Lab Unveils Novel System for Regulating Gene Expression with Heat

September 30, 2020 | Categories: Research, Uncategorized | Tagged: 3D Printing, gene expression, Liver, Stevens, tissue engineering

Researchers hoping to create disease models or regenerate organs need systems that precisely mimic the degree of complexity found in the natural world. The Stevens Lab is helping to answer the call with a new system that regulates gene expression patterns using heat Read More

A glowing, glittery ring with purple and green specks floats against a black background, forming a smooth, continuous circular shape.

Zheng Lab Uses New 3D Model to Study Effect of Curvature on Endothelial Cells

September 16, 2020 | Categories: Research | Tagged: blood vessels, endothelial, tissue models, Zheng

Every day, million of cars navigate a complex network of wide, straight highways, busy streets and avenues, and side roads that bend and curve in unpredictable patterns. Now a new 3D modeling tool will help scientists study even more complex traffic patterns at work in our blood vessels. Read More

Fluorescence microscopy image of cells with irregular, interconnected shapes outlined in green, red, and blue, against a dark background, highlighting the cellular membrane structures.

Color-Coding Technology Reveals New Insights About Stem Cell Biology

July 29, 2020 | Categories: Research | Tagged: Davis, neurons, Rainbow Reporters, Stem Cells

Several years ago, Danny El-Nachef was given a mission to create a tool to observe and track how stem cells behaved during the earliest stages of human heart development. While the focus of the challenge was human biology, the x-factor in the solution came from the sea. Read More

A collage of twelve smiling young adults, arranged in three rows, with the text FY21 ISCRM Fellows on a purple background in the bottom right corner.

Meet the FY21 ISCRM Fellows

July 8, 2020 | Categories: Award

Various petri dishes containing intricate, abstract 3D-printed objects in white and off-white tones are displayed on a dark surface, showcasing different geometric and organic designs.

Sweet way to 3D-print Blood Vessels

June 30, 2020 | Categories: Research | Tagged: 3D Printing, Stevens

A collage of seven people, including four men and three women, posing for individual portraits. One woman is in a lab coat using lab equipment; others are smiling at the camera in various indoor settings.

Announcing the FY21 Innovation Pilot Award Recipients

June 26, 2020 | Categories: Announcements, Award | Tagged: Cirulli, Folch, Kelly, Roy, Seslar, Silberstein, Watson

Side-by-side portraits of a man with curly dark hair wearing a brown jacket and a woman with short brown hair wearing a black top with a patterned shoulder design and a necklace. Both are facing the camera and smiling slightly.

Improving Islet Transplantation to Treat Type 1 Diabetes

June 22, 2020 | Categories: Award | Tagged: biomaterials, Cirulli, Crisa, DeForest, diabetes, islet, transplantation

A major grant from the NIH will allow three ISCRM investigators to use their combined expertise in islet and stem cell biology, vascular biology and cellular immunology, and biomaterials to significantly improve the wellbeing of people with type 1 diabetes. Read More

Fluorescent microscopy image showing branching red structures, green spots, and blue oval shapes, likely representing stained cells with visible nuclei. Black background highlights the cell structures.

Young Lab Links Loss of SORL1 Gene to Increased Alzheimer’s Risk

June 2, 2020 | Categories: Research | Tagged: Alzheimers, CRISPR, neurons, Young

To overcome the inherent challenges in studying the brain, one ISCRM team used stem cell technology to implicate a gene known as SORL1 in some types of Alzheimer’s and to shed new light on why many promising treatments for this disease have hit dead ends in clinical trials. Read More

Fluorescent image of a zebrafish larva viewed from the side (top) and above (bottom), showing green fluorescence highlighting skeletal structures. Text in the corner reads sp7:EGFP autofluorescence.

NIH Funds Kwon Lab Effort to Identify Genetic Risk Factors for Osteoprosis

May 18, 2020 | Categories: Award, Research | Tagged: Kwon, osteoporosis, zebrafish

Q&A with Erica Jonlin PhD, Author of Perspective on Informed Consent Published in Stem Cell Reports

April 14, 2020 | Categories: Administrative Staff | Tagged: genome editing, informed consent, Jonlin

Background In November 2018, Dr. He Jiankui used a series of YouTube videos to announce the birth of the world’s first genetically-modified babies, twin girls who soon became known as […] Read More

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