New cell lines will allow researchers to probe the basic biology of Alzheimer’s. Currently, however, there are no treatments that can prevent or slow the progression of this memory-robbing disease, which affects more than 5 million Americans. One reason for this is that we really don’t know the cause of Alzheimer’s: It is known that brain cells that are crucial to forming new memories die. But we don’t know why. Read More
On May 9, 2018, three new ISCRM human embryonic stem cell (hESC) lines were accepted onto the NIH Stem Cell Registry. Originated from donated human preimplantation blastocysts, Carol Ware derived the lines in medium that halted development in a preimplantation stage so they maintained a naive character. All three lines have a good karyotype. The cell […] Read More
A robotic approach to mass-producing organoids could accelerate regenerative medicine research and drug discovery. An automated system that uses robots has been designed to rapidly produce human mini-organs derived from stem cells. Researchers at the University of Washington School of Medicine in Seattle developed the new system. Read More
On Thursday, March 22, Governor Inslee signed into law House Bill 2356. This legislation will require Washington State “stem-cell clinics” to post a visible notice that their injection procedures are not FDA-approved and that patients should consult with primary-care providers before undergoing one. Read More
The University of Washington is saying goodbye to a wonderful friend and alumnus in Orin Smith. Orin’s involvement in numerous areas left an indelible mark on the University, and we were exceptionally fortunate to benefit from his leadership and support at ISCRM for more than a decade. In fact, Orin was one of the earliest supporters of ISCRM and the creation of the UW Medicine South Lake Union Campus. Read More
Improving the trafficking of cellular proteins in brain cells holds possibilities for new treatments and even prevention for Alzheimer’s disease, results of a new study suggest. Researchers found that a compound that enhances the shuttling of proteins within cells reduced the production of forerunners of two proteins implicated in brain cell death. Read More
Congratulations to this year’s winners of the 2018 Travel Awards. Each travel award is in the amount of $1,000 to be applied toward travel to the June 2018 ISSCR meeting in Melbourne, Australia. Read More
Drug treatments can save lives, but sometimes they also carry unintended costs. After all, the same therapeutics that target pathogens and tumors can also harm healthy cells. To reduce this collateral damage, scientists have long sought specificity in drug delivery systems: A package that can encase a therapeutic and will not disgorge its toxic cargo until it reaches the site of treatment — be it a tumor, a diseased organ or a site of infection. Read More
Researchers built an algorithm to discern which drugs might best combat patients’ individual cases of acute myeloid leukemia. The statistics are grim. For patients fighting an aggressive form of leukemia known as acute myeloid leukemia, or AML, doctors over the last 40 years have usually used a combination of two drugs to fight the disease, but it seldom cures it. Read More
A therapy developed at UW shows promise in its first test in young boys who have an inherited deadly muscle disease. Favorable interim results have been announced in a small clinical trial of a stem-cell therapy to treat patients with a rare, deadly disease called myotubular myopathy. Read More
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