Core Overview (Genomics & Stem Cell)
Core Overview (Genomics & Stem Cell)
Julie Mathieu, PhD "Ellison Stem Cell Core" Mary Regier, PhD "ISCRM Genomics Core Update"
Over the last decade, human induced pluripotent stem cells (iPSCs) have become powerful tools of discovery for scientists around the world. Read More
Myelodysplastic syndromes (MDS) are heterogenous blood disorders that affect up to 170,000 people in the United States, primarily over the age of 60. While early symptoms, including anemia (characterized by fatigue), are not serious, MDS is a high-risk factor for leukemia. Currently there are few treatment for MDS and the causes remain poorly understood. Read More
Heart failure is a widespread chronic condition that directly impacts nearly six million Americans, contributes to almost one in ten deaths in the United States, and drains an estimated $30 billion annually from our national economy. Read More
Bioengineers have cleared a major hurdle on the path to 3D printing replacement organs with a breakthrough technique for bioprinting tissues. The new innovation allows scientists to create exquisitely entangled vascular networks that mimic the body's natural passageways for blood, air, lymph and other vital fluids. Read More
Deep in the inner ear, at the base of the semicircular canals, sit tiny vestibular organs called crista ampullaris – or crista, for short. Aided by millions of sensory hair cells, crista help us maintain our gaze as we move through space, not unlike a stabilizer function in a modern camera. Without a healthy population of these hair cells, the brain struggles to remain oriented and to track its position relative to the surrounding world that our eyes and ears perceive. Read More
While prostate cancer may not be as deadly as other cancers – five-year survival rates can exceed 90%, especially if the disease is localized – incidence rates overall are increasing. For 2019 alone, The American Cancer Society predicts the United States will see roughly 175,000 new cases and 32,000 deaths associated with prostate cancer. Read More
Long before Hannele Ruohola-Baker became a leading stem cell researcher, she was a young hockey player skating on the frozen ponds of her native Finland. When she was ten years old, she lost a tooth to an errant puck. “I’d say that’s when my interest in regenerating teeth began,” says Dr. Ruohola-Baker, now a Professor of Biochemistry and Associate Director of the UW Medicine Institute for Stem Cell and Regenerative Medicine (ISCRM). Read More
February 7, 2019 Of all the mysteries surrounding the beginning of human life, one question has drawn particular interest from researchers at the Institute for Stem Cell and Regenerative Medicine […] Read More
February 4, 2019 Heart failure is the leading cause of death in the world. In the United States alone, hundreds of thousands of people succumb to the disease every year, […] Read More
February 1, 2019 Experimental gene therapy cassettes for Duchenne muscular dystrophy have been modified to deliver better performance. The cassettes, which carry the therapy into muscle cells, contain newer versions […] Read More