News

A small, translucent, 3D-printed plastic object with a rectangular base, two vertical supports, and an oval-shaped top piece, placed on a gray surface.

User-Friendly 3D-Printed Device Will Allow Researchers to Model Human Tissue With Increased Control and Complexity

April 30, 2025 | Categories: Core Faculty, Research, Uncategorized | Tagged: , ,

The device known as STOMP, developed by researchers from the Sniadecki and Theberge Labs, is small enough to fit on a human fingertip and is compatible with existing tissue engineering technology. Read More

Diagram showing cellular trafficking pathways involving SORL1, VPS26a, and VPS26b between the trans-Golgi network, early endosome, and lysosome, with notes on how SORL1 loss affects neurons and microglia.

How Cellular Dysfunction Associated with Alzheimer’s Disease Arises in Microglia  

April 17, 2025 | Categories: Core Faculty | Tagged: ,

New research from the lab of ISCRM faculty member Jessica Young sheds light on the relationship between loss of SORL1 and Alzheimer's disease risk specifically in microglia. Read More

A gloved hand holds two clear plastic squares containing rows of colorful dots, likely samples or wells, inside a petri dish. The background and glove are tinted blue.

New Platform for Tissue Engineers Reduces Guesswork in Bioink Formulation

April 11, 2025 | Categories: Core Faculty, Uncategorized | Tagged: , ,

The Stevens Lab has unveiled a game-changing system to simultaneously screen dozens of varying compositions of bioinks for tissue and organ printing Read More

Microscope image of a worm section showing cells outlined in gray, with red and green fluorescent markers highlighting specific features along the outer edge of the body.

Reh Lab Shows Conclusively that AAV-delivered Genes Can Regenerate Mammalian Retinal Neurons

March 24, 2025 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

Researchers in the Reh Lab have produced the clearest evidence yet that AAV-delivered genes can stimulate regeneration in the mammalian retina Read More

Fluorescent microscopic image of a circular group of cells with green, blue, and purple highlights on a black background, showing cell boundaries and internal structures.

Freedman Lab Tests a Promising mTOR Inhibitor in PKD Organoids

January 23, 2025 | Categories: Research | Tagged: , , ,

The study results suggest the molecule at the center of the study may be safer at higher doses and therefore more potent against harmful cysts. Read More

Side-by-side portraits of a man in glasses and a white coat, smiling, and a woman with curly hair in a dark blazer, also smiling, both in professional settings.

Yang Lab Co-Leads NIH-Funded Effort to Improve Genetic Testing for HCM

November 4, 2024 | Categories: Research | Tagged: , , ,

An NIH-funded partnership between ISCRM faculty member Dr. Daniel Yang and Dr. Lea Starita in the UW Department of Genome Sciences will use an innovative gene editing technology to sequence large numbers of variants of a mutation associated with hypertrophic cardiomyopathy. Read More

Color-coded diagram of a protein structure with labeled regions: Upper 50 kDa (blue), Lower 50 kDa (light blue), Actin Binding Sites (green), Regulatory Loops (red), N-Terminal Domain (purple), Relay Helix (red), Converter Domain (orange).

How Small Molecules Have a Big Impact on the Heart

October 23, 2024 | Categories: Core Faculty, Research | Tagged: , , ,

Researchers at UW and UCSD use a multiscale modeling tool show how small infusions of myosin can have a big impact on the whole heart. Read More

Four panels show the same bone structure in blue, red, green, and purple against a black background, highlighting detailed textures and variations in the bone’s surface.

Modeling the Periodontal Ligament in 3D

October 22, 2024 | Categories: Core Faculty, Research | Tagged: ,

A new 3D modeling tool developed by the Sniadecki Lab and Dr. Tracy Popwics in the School of Dentistry could lead to regenerative therapies for periodontal diseases. Read More

Headshot of David Baker

David Baker Receives Nobel Prize

October 9, 2024 | Categories: Award, Core Faculty | Tagged:

ISRCRM faculty member David Baker has been awarded the 2024 Nobel Prize in Chemistry for computational protein design. Read More

Two men wearing white lab coats stand and smile in a laboratory. Shelves with lab equipment and supplies are visible in the background, and a window lets in natural light.

New Gene Therapy for Muscular Dystrophy Offers Hope

July 17, 2024 | Categories: Core Faculty, Research | Tagged: , ,

A new gene therapy treatment for Duchenne muscular dystrophy (DMD) shows promise of not only arresting the decline of the muscles of those affected by this inherited genetic disease, but perhaps, in the future, repairing those muscles. Read More

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