News

ISCRM Researchers to Play Pivotal Roles on NIH-Funded Collaboration with Stanford

July 10, 2019 | Categories: Announcements, Award, Core Faculty | Tagged: , , , , , ,

Over the last decade, human induced pluripotent stem cells (iPSCs) have become powerful tools of discovery for scientists around the world. Read More

Research from Doulatov Lab in the Journal Blood Offers Stem Cell-Aided Insights on MDS Onset

June 13, 2019 | Categories: Research | Tagged: , ,

Myelodysplastic syndromes (MDS) are heterogenous blood disorders that affect up to 170,000 people in the United States, primarily over the age of 60. While early symptoms, including anemia (characterized by fatigue), are not serious, MDS is a high-risk factor for leukemia. Currently there are few treatment for MDS and the causes remain poorly understood. Read More

New Findings About dATP-Enhanced Heart Contractions Published in PNAS

May 21, 2019 | Categories: Core Faculty, Research | Tagged: , , , , ,

Heart failure is a widespread chronic condition that directly impacts nearly six million Americans, contributes to almost one in ten deaths in the United States, and drains an estimated $30 billion annually from our national economy. Read More

Breakthroughs in 3D Organ Printing Detailed in Science

May 2, 2019 | Categories: Core Faculty, Research | Tagged: , , ,

Bioengineers have cleared a major hurdle on the path to 3D printing replacement organs with a breakthrough technique for bioprinting tissues. The new innovation allows scientists to create exquisitely entangled vascular networks that mimic the body's natural passageways for blood, air, lymph and other vital fluids. Read More

Major NIH Grant Funds a Closer Look at Understudied Sensory Hair Cells Crucial for Balance

April 15, 2019 | Categories: Announcements, Award | Tagged:

Deep in the inner ear, at the base of the semicircular canals, sit tiny vestibular organs called crista ampullaris – or crista, for short. Aided by millions of sensory hair cells, crista help us maintain our gaze as we move through space, not unlike a stabilizer function in a modern camera. Without a healthy population of these hair cells, the brain struggles to remain oriented and to track its position relative to the surrounding world that our eyes and ears perceive. Read More

Studying Cell Signaling in the Prostate

| Categories: Core Faculty, Research | Tagged: , , ,

While prostate cancer may not be as deadly as other cancers – five-year survival rates can exceed 90%, especially if the disease is localized – incidence rates overall are increasing. For 2019 alone, The American Cancer Society predicts the United States will see roughly 175,000 new cases and 32,000 deaths associated with prostate cancer. Read More

ISCRM and the UW School of Dentistry Reveal Important New Findings About the Nature of Stem Cells in Human Teeth

February 22, 2019 | Categories: Research | Tagged: , , ,

Long before Hannele Ruohola-Baker became a leading stem cell researcher, she was a young hockey player skating on the frozen ponds of her native Finland. When she was ten years old, she lost a tooth to an errant puck. “I’d say that’s when my interest in regenerating teeth began,” says Dr. Ruohola-Baker, now a Professor of Biochemistry and Associate Director of the UW Medicine Institute for Stem Cell and Regenerative Medicine (ISCRM). Read More

Aided by Stem Cells, ISCRM Researchers Identify a Suspect in the Case of Infertility

February 7, 2019 | Categories: Core Faculty, Research | Tagged: ,

February 7, 2019 Of all the mysteries surrounding the beginning of human life, one question has drawn particular interest from researchers at the Institute for Stem Cell and Regenerative Medicine (ISCRM). Simply put, for women who are unable to get pregnant, what is happening at the cellular level that is preventing life from taking hold? […] Read More

ISCRM Labs Collaborate to Grow Heart Tissue In Vitro

February 4, 2019 | Categories: Research | Tagged: , , ,

February 4, 2019 Heart failure is the leading cause of death in the world. In the United States alone, hundreds of thousands of people succumb to the disease every year, while the costs of care and lost productivity drain more than $200 billion from the economy. Recent breakthroughs in stem cell research offer hope for […] Read More

Gene Therapy Cassettes Improved for Muscular Dystrophy

February 1, 2019 | Categories: Research | Tagged: , , ,

February 1, 2019 Experimental gene therapy cassettes for Duchenne muscular dystrophy have been modified to deliver better performance.  The cassettes, which carry the therapy into muscle cells, contain newer versions of a miniaturized treatment gene. The micro-dystrophin, as the treatment gene is called, has been restructured to enhance its functionality. The revamped versions were developed […] Read More

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