News

Three people wearing white lab coats closely examine scientific equipment on a lab bench, appearing focused and engaged in a laboratory setting.

Kelly Stevens to Co-Lead NIH Funded Center to Foster New Ideas and Fight Inequity

June 27, 2024 | Categories: Core Faculty | Tagged: ,

Kelly Stevens and Lola Eniola-Adefeso at the University of Michigan are co-leaders of a new NIH-funded center that will spur biomaterials translational solutions and bring together traditional, nontraditional, and historically excluded biomaterials researchers. Read More

Microscopic image showing a cell with branching white structures on the left, and a 3D molecular model with a white circular structure and pink segments on the right, set against a dark background.

Designed Proteins Guide Stem Cells to Form Blood Vessels

June 11, 2024 | Categories: Core Faculty, Research | Tagged: , ,

UW researchers have used computer-designed proteins to direct human stem cells to form new blood vessels in the lab, offering new hope for repairing damaged hearts, kidneys, and other organs. Read More

Side-by-side photos of two men: the left man with short light brown hair wearing a light purple shirt, and the right man with short dark curly hair wearing a dark polo shirt, smiling in a room with shelves behind him.

Meet the 2024 Tietze Award Winners

May 24, 2024 | Categories: Award, Core Faculty | Tagged: , ,

ISCRM Associate Director Nate Sniadecki, PhD, Professor of Mechanical Engineering and Hichem Tasfaout, PhD, Acting Assistant Professor, Neurology have received prestigious awards from the John H. Tietze Foundation Trust that will help fuel promising research underway in their labs. Read More

Illustration of microscopic muscle fibers and proteins, showing bundled orange filaments with spiral extensions and rows of green and purple molecules, representing molecular processes within muscle tissue.

Why Tiny Changes in Protein Structure Can Lead to Big Problems for the Heart

May 2, 2024 | Categories: Research, Uncategorized | Tagged: , , ,

An NIH-funded collaboration involving ISCRM researchers has published a study describing how complementary areas of expertise produced new insights about hypertrophic cardiomyopathy at the protein, cell, and tissue levels. Read More

Side-by-side images of PKD mini-kidneys: the untreated one (left) appears smoother, while the one given readthrough drug (right) looks more structured or textured. Each is about 1mm wide.

Freedman Lab Discovers Promising New Therapeutic for PKD in Tailor-Made Organoids

April 4, 2024 | Categories: Core Faculty, Research | Tagged: , , ,

In a new study published in Cell Stem Cell, the Freedman Lab shows that a drug known to be safe in humans inhibits the growth of cysts in gene-edited organoids with polycystic kidney disease. Read More

Nine people sit at the front of a lecture hall while a woman stands and presents a Parkinsons disease research slide with trial details and results projected on a screen behind them.

Stem Cells in Clinical Trials

April 1, 2024 | Categories: Uncategorized

On Thursday, March 6, ISCRM hosted Stem Cells in Clinical Trials: A Panel Discussion on Progress in the Field of Regenerative Medicine. Summaries of the presentations and a recording of the event are now available. Read More

A middle-aged man with short, light brown hair smiles at the camera while wearing a white button-up shirt against a plain gray background.

Leadership News

| Categories: Core Faculty

ISCRM Dr. Charles “Chuck” Murry has been appointed to lead stem-cell research at the University of Southern California’s Keck School of Medicine. He will start there in August. Read More

Two scientists in lab coats and gloves sit in a laboratory with scientific equipment, a microscope, and computers displaying data on screens. Shelves with lab supplies and boxes are visible in the background.

Berndt Lab Machine Learning Model Sets a New Pace in Protein Sensor Design

March 26, 2024 | Categories: Core Faculty, Research | Tagged: , ,

Over the course of a multiyear, collaborative investigation, researchers in the Berndt Lab showed that their trained machine learning models correctly predicted several variants of the calcium indicator GCaMP with record-setting speed and accuracy, outperforming all previous generations of these sensors. Read More

Diagram showing a coil-flanked XTEN protein with stabilizing mutations, forming an injectable protein gel that exhibits self-healing, shear-thinning, and supports high cell viability, with a close-up of green cells.

Protein-Based Biomaterial Protects Injected Cells, Improves Engraftment

March 13, 2024 | Categories: Core Faculty, Research | Tagged: , , , ,

Research led by Cole DeForest, PhD in collaboration with Chuck Murry, MD, PhD and Kelly Stevens, PhD details a new protein-based biomaterial that could help improve engraftment and function following injectable cell therapies. Read More

Gloved hands holding and assembling scientific equipment with transparent chambers and labeled cassette, likely used for laboratory experiments or cell culture work.

$7.3 Million NIH Grant Funds Effort to Advance Kidney Microphysiological Testing Platforms

February 12, 2024 | Categories: Core Faculty, Research | Tagged: , , , , ,

NIH Funding will allow ISCRM faculty members Ed Kelly and Beno Freedman to lead the effort to advance kidney-on-a-chip and organoid testing technology and submit a 3D engineered platform for FDA approval. Read More

Calendar

Events

Calendar of Events

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
0 events,
View Calendar
See All Events