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Meet the 2022-2023 ISCRM Fellows

August 1, 2022 | Categories: Award, Research, Uncategorized | Tagged: , ,

State-funded ISCRM Fellowships enable students at the undergraduate, graduate, and postdoctoral level to advance research efforts aimed at addressing the root causes of diseases. Read More

Faculty headshot of Thelma Escobar, PhD

Grant for Escobar Lab Funds AML Research

July 13, 2022 | Categories: Award, Core Faculty, Research | Tagged: , , , , ,

Thelma Escobar, PhD is collaborating with the Doulatov Lab and the Stem Cell Core to study how mutations in the gene NPM1 drive AML onset. Read More

Faculty headshot of Patrick M. Boyle, PhD, PEng, FHRS

Boyle Lab Leads Effort to Improve Stroke Risk Assessment

July 5, 2022 | Categories: Award, Core Faculty, Research | Tagged: ,

ISCRM faculty member Patrick Boyle has received a five-year, $2.9 million grant from the National Heart, Lung, and Blood Institute to improve outcomes for stroke patients by identifying and testing individualized strategies for diagnosing and treating strokes. Read More

Francisco Saavedra Cantillana is a Pew Latin American Fellow

June 30, 2022 | Categories: Award | Tagged: , ,

Francisco Saavedra Cantillana PhD, a Postoc in the Escobar Lab, has been named one of ten 2022 Pew Latin American Fellows in the Biomedical Sciences. Read More

Laura Crisa and Farid Moussavi-Harami Receive Tietze Awards

June 3, 2022 | Categories: Award, Core Faculty | Tagged: , , ,

Laura Crisa, MD, PhD and Farid Moussavi-Harami, MD have received prestigious awards from the John H. Tietze Foundation Trust that will help fuel promising research underway in their labs. Read More

Primary cilia (red) lining the surface of human kidney organoids (gray).

Freedman Lab Explores the Role Cilia Play in Signaling, Cell Fate, and Disease Development

April 27, 2022 | Categories: Research | Tagged: , , , , , ,

In the Freedman Lab, knocking out primary cilia reveals insights about the role the organelles play in cell fate and disease development. Read More

Deletion of Lamin B1 Linked to Nuclear Abnormalities Seen in Cancer

March 11, 2022 | Categories: Research, Uncategorized | Tagged: , ,

Using gene-editing tools to decrease expression of lamin B1 in two stem cell models, the researchers show that deletion of lamin B1 causes change in stem cell function and nuclear shape – and contributes to leukemia progression. Read More

Regulating Cells With Designed Proteins

March 1, 2022 | Categories: Core Faculty, Research | Tagged: , , , ,

ISCRM researchers have developed a tool to selectively control the PRC2 complex – an epigenetic regulator that influences cell fate across multiple stages of development. That tool is a computer-designed protein binder engineered in partnership with the Institute for Protein Design (IPD). Read More

Faculty headshot of Kelly R. Stevens, PhD

Kelly Stevens Elected to American Institute for Medical and Biological Engineering

February 18, 2022 | Categories: Announcements, Core Faculty | Tagged:

Stevens, an assistant professor of bioengineering and of laboratory medicine and pathology, was selected for her work on pioneering approaches to map and replicate human tissues to advance bioengineered organs toward clinical therapy. Read More

Davis Lab Examines a Protein With a Key Role in Scarring

February 16, 2022 | Categories: Core Faculty, Research | Tagged: , ,

In a study that came with some unexpected findings, ISCRM researchers reveal new details about the role an RNA binding protein (MBNL1) plays in the steps that lead to scarring in the heart. Read More

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