Microscopic image showing clusters of oval and round yeast cells, highlighted with yellow fluorescence, on a dark background.

Kueh Lab Studies How and When Immune Cells Form Pathogen Memories

February 1, 2024 | Categories: Core Faculty, Research | Tagged: ,

Research from the Kueh Lab shows infection-fighting blood cells can change course to become long-lived memory cells instead of short-lived killer cells. Read More

Four panels show the same two T cells labeled with different markers: Erk (cyan), NFAT (red), H2B (magenta), and a grayscale brightfield image. Each cell outline is highlighted with a white dotted line.

Study from Kueh Lab Describes Surprising Agility in T Cell Threat Assessment

January 11, 2024 | Categories: Core Faculty, Research | Tagged: , ,

New research from the Kueh Lab, published in the journal PNAS, reveals surprising insights about the signaling circuitry that allows T cells to elicit tailored responses to a diverse range of threats and proposes a model for future study. Read More

Side-by-side portraits of two women; the left woman has short gray hair, glasses, and a white lab coat, while the right woman has long brown hair and is wearing a teal top, smiling at the camera.

Finding a Sweet Spot for Cultivating Embryonic Cell Lines

January 2, 2024 | Categories: Core Faculty, Research | Tagged: , ,

Research from Julie Mathieu and Carol Ware adds to understanding of human early development and the clinical utility of late naïve hESC derived directly from blastocysts. Read More

A woman with long, straight dark hair is smiling at the camera. She is wearing a navy blue blazer over a white top and is posed in front of a plain gray background.

Welcome Yusha “Katie” Liu

| Categories: Core Faculty, Research | Tagged: , , ,

Dr. Yusha “Katie” Liu joined ISCRM in 2023 as an Assistant Professor in the Division of Plastic Surgery, Department of Surgery Read More

Diagram illustrating 3D brain microvessels under different conditions: resting, after 8 hours with TNF, and after 8 and 24 hours with parasites, showing changes like microparticles, gaps, filaments, and ghost cells.

Zheng Lab Unveils Platform for Modeling Cerebral Malaria in 3D

November 20, 2023 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

A new paper from the Zheng Lab, published in Cell Reports, unveils a technique for probing cerebral malaria inflammation in 3D engineered human brain microvessels. Read More

A woman with straight, shoulder-length black hair smiles at the camera. She is wearing a dark green blouse and a turquoise pendant necklace, standing in front of a gray background.

Introducing Feini (Sylvia) Qu

September 22, 2023 | Categories: Core Faculty | Tagged: , ,

ISCRM faculty member Feini (Sylvia) Qu will explore the cellular and molecular pathways of composite musculoskeletal tissue regeneration, especially the bones and connective tissues that link our limbs and joints. Read More

Fluorescent microscopy image of a tissue section showing a triangular structure with layers of blue, green, yellow, and magenta cells. Blue dots, likely cell nuclei, are scattered throughout. A scale bar indicates 50 micrometers.

Stem Cell-derived Organoids Secrete Tooth Enamel Proteins

August 14, 2023 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

Researchers led by Hannele Ruohola-Baker have created organoids from stem cells that secrete the proteins that form the enamel that protects our teeth from damage and decay. Read More

A smiling man with short brown hair and glasses, wearing a dark shirt and lanyard, stands indoors in front of a window with green foliage visible outside.

FDA Approves Gene Therapy with ISCRM Origins

July 5, 2023 | Categories: Core Faculty, Research | Tagged: , , ,

The FDA has approved a first-ever gene therapy for Duchenne muscular dystrophy based in part on technology developed by UW Medicine/ISCRM Researchers Read More

Two people are shown side by side. On the left, a woman with shoulder-length brown hair sits at a desk, smiling, with papers in front of her. On the right, a man with short hair smiles while sitting in an office.

Meet the 2023 Tietze Award Winners

June 1, 2023 | Categories: Award, Core Faculty, Research, Uncategorized | Tagged: , , ,

Julie Mathieu, PhD and Niclas Bengtsson, PhD have received prestigious awards from the John H. Tietze Foundation Trust that will help fuel promising research underway in their labs. Read More

Fluorescent microscope image of intestinal tissue showing finger-like villi structures; cell nuclei appear blue, cell membranes green, and certain cells or features highlighted in red.

Study From Moltke Lab Describes How Immune Sentinel Tuft Cells Differentiate From Epithelial Stem Cells

May 12, 2023 | Categories: Core Faculty, Research | Tagged: ,

New research from the Moltke Lab at UW Medicine describes how our body generates an enigmatic cell type, known as tuft cells, that detects parasitic worms and helps to mobilize an immune response. Read More