Regulating Cells With Designed Proteins

March 1, 2022 | Categories: Core Faculty, Research | Tagged: , , , ,

ISCRM researchers have developed a tool to selectively control the PRC2 complex – an epigenetic regulator that influences cell fate across multiple stages of development. That tool is a computer-designed protein binder engineered in partnership with the Institute for Protein Design (IPD). Read More

Faculty headshot of Kelly R. Stevens, PhD

Kelly Stevens Elected to American Institute for Medical and Biological Engineering

February 18, 2022 | Categories: Announcements, Core Faculty | Tagged:

Stevens, an assistant professor of bioengineering and of laboratory medicine and pathology, was selected for her work on pioneering approaches to map and replicate human tissues to advance bioengineered organs toward clinical therapy. Read More

Davis Lab Examines a Protein With a Key Role in Scarring

February 16, 2022 | Categories: Core Faculty, Research | Tagged: , ,

In a study that came with some unexpected findings, ISCRM researchers reveal new details about the role an RNA binding protein (MBNL1) plays in the steps that lead to scarring in the heart. Read More

Kelly Stevens receives $1.3M Allen Distinguished Investigator Award to study how liver develops

February 9, 2022 | Categories: Award, Core Faculty, Research | Tagged: , ,

Kelly Stevens has received an Allen Distinguished Investigator Award to support her work to map and understand how human livers develop. Read More

Green and purple stained organoid

ISCRM Research Sheds New Light on COVID-19 and Kidney Health

December 2, 2021 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

ISCRM researchers use kidney organoids to demonstrate that COVID-19 is capable of infecting kidney cells directly and test whether a synthetic protein designed by the Institute for Protein Design (IPD) might be capable of preventing infection. Read More

three scientists in a lab

Undergraduate Students on the Hunt for Cancer Killing Molecules

November 3, 2021 | Categories: Core Faculty | Tagged: , ,

Described in the journal Cells, a multi-year effort to identify molecules that target cancer cells gave UW undergraduates real-world laboratory experience. Read More

purple and blue stained retinal cells

Nudging Cells to Repair Damaged Retinas

October 25, 2021 | Categories: Core Faculty, Research | Tagged: , , ,

Researchers led by ISCRM faculty member Tom Reh induce support cells in the retina to become neurons, an approach that someday could help restore vision. Read More

grid of scientists

Watch a Brief Video About ISCRM

September 17, 2021 | Categories: Core Faculty, Research

Watch this brief video about the collaborative research community harnessing advances in biology and engineering to confront the root causes of disease. Read More

ISCRM Researchers Part of $56 Million Grant to Fund Alzheimer’s Research

September 3, 2021 | Categories: Core Faculty | Tagged: , ,

The five-year grant awarded to the Kaiser Adult Changes in Thought study (ACT) will fund six cores and three interrelated research projects. Read More

Faculty headshot of Kelly R. Stevens, PhD

W.M. Keck Foundation Funds Liver Research in Stevens Lab

September 2, 2021 | Categories: Core Faculty | Tagged: ,

A three-year grant from the W.M. Keck Foundation will fund a three-year effort by the Stevens Lab to shed light on the role of mechanical factors in liver regeneration. Read More