Special Issue in Frontiers in Cell and Developmental Biology Edited by David Mack, Mark Bothwell, and Alec Smith
October 14, 2022 | Categories: UncategorizedDavid Mack, Mark Bothwell, and Alec Smith are the editors of a special issue of Frontiers in Cell & Developmental Biology that explores different models for investigating neuromuscular disease and weighing the pros and cons of stem cell-based models versus cell lines and animal models. Read More
Modeling a Muscle Disease in 3D
August 17, 2022 | Categories: Award, Core Faculty, Research, Uncategorized |A team of investigators led by ISCRM faculty members David Mack, PhD and Nate Sniadecki, PhD have shown that is possible to recreate DMD with much more complexity in a 3D model of engineered heart tissue. Read More
Meet the 2022-2023 ISCRM Fellows
August 1, 2022 | Categories: Award, Research, Uncategorized |State-funded ISCRM Fellowships enable students at the undergraduate, graduate, and postdoctoral level to advance research efforts aimed at addressing the root causes of diseases. Read More
Deletion of Lamin B1 Linked to Nuclear Abnormalities Seen in Cancer
March 11, 2022 | Categories: Research, Uncategorized |Using gene-editing tools to decrease expression of lamin B1 in two stem cell models, the researchers show that deletion of lamin B1 causes change in stem cell function and nuclear shape – and contributes to leukemia progression. Read More
ISCRM Research Sheds New Light on COVID-19 and Kidney Health
December 2, 2021 | Categories: Core Faculty, Research, Uncategorized |ISCRM researchers use kidney organoids to demonstrate that COVID-19 is capable of infecting kidney cells directly and test whether a synthetic protein designed by the Institute for Protein Design (IPD) might be capable of preventing infection. Read More
Meet the 2021-2022 ISCRM Fellows
September 14, 2021 | Categories: UncategorizedThe 2021-2022 ISCRM Fellows were selected from a deep pool of undergraduate students, PhD students, and postdoc. Each ISCRM Fellow has received a state-funded fellowship to support their research. Read More
Gene Editing May Help Address Arrhythmia Challenges in Heart Regeneration
June 21, 2021 | Categories: Heart Regeneration, Research, Uncategorized |New data presented by ISCRM Director Chuck Murry suggests gene-editing may be the key to clearing a major hurdle for researchers hoping to remuscularize injured hearts with stem cell-derived cardiomyocytes Read More
Andrea Wills and Daniel Yang Receive Tietze Research Awards
May 13, 2021 | Categories: Uncategorized
ISCRM Welcomes Thelma Escobar
May 6, 2021 | Categories: UncategorizedThelma Escobar, PhD, joins the University of Washington as an Assistant Professor of Biochemistry and an ISCRM faculty member Read More
Study Yields New Clue to Strokes of Undetermined Source
May 4, 2021 | Categories: Core Faculty, Research, Uncategorized |Simulations shed light on heart-scarring similarities among patients with atrial fibrillation and those who had embolic stroke but no atrial fibrillation. Read More