Diagram illustrating 3D brain microvessels under different conditions: resting, after 8 hours with TNF, and after 8 and 24 hours with parasites, showing changes like microparticles, gaps, filaments, and ghost cells.

Zheng Lab Unveils Platform for Modeling Cerebral Malaria in 3D

November 20, 2023 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

A new paper from the Zheng Lab, published in Cell Reports, unveils a technique for probing cerebral malaria inflammation in 3D engineered human brain microvessels. Read More

Fluorescent microscopy image of a tissue section showing a triangular structure with layers of blue, green, yellow, and magenta cells. Blue dots, likely cell nuclei, are scattered throughout. A scale bar indicates 50 micrometers.

Stem Cell-derived Organoids Secrete Tooth Enamel Proteins

August 14, 2023 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

Researchers led by Hannele Ruohola-Baker have created organoids from stem cells that secrete the proteins that form the enamel that protects our teeth from damage and decay. Read More

Side-by-side portraits of a woman with straight dark hair, wearing a sleeveless top, and a man with short dark hair, wearing a blue shirt. Both are facing forward and smiling.

Welcome Min (Mia) Yang and Nobuhiko (Nobu) Hamazaki

August 8, 2023 | Categories: Uncategorized

ISCRM is thrilled to welcome two new faculty members, Min (Mia) Yang, Assistant Professor, OBGYN and Nobuhiko (Nobu) Hamazaki, PhD, Assistant Professor, OBGYN and Genome Sciences. Read More

Two people are shown side by side. On the left, a woman with shoulder-length brown hair sits at a desk, smiling, with papers in front of her. On the right, a man with short hair smiles while sitting in an office.

Meet the 2023 Tietze Award Winners

June 1, 2023 | Categories: Award, Core Faculty, Research, Uncategorized | Tagged: , , ,

Julie Mathieu, PhD and Niclas Bengtsson, PhD have received prestigious awards from the John H. Tietze Foundation Trust that will help fuel promising research underway in their labs. Read More

A smiling man in a blue plaid shirt and gray cardigan sits beside a laboratory biosafety cabinet with colorful lab racks and containers inside.

Breaking Boundaries in Skin Research With Biosensors and Optogenetics

April 14, 2023 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

Cory Simpson, MD, PhD and Andre Berndt, PhD detail how advances in biosensor and optogenetic technology are opening up new possibilities in dermatology research. Read More

Two scientists wearing white lab coats, purple face masks, and gloves work in a laboratory; one operates equipment under a fume hood while the other observes closely.

Gene-Edits Safely Reduce Irregular Heartbeats in Cell Therapy for Heart Disease

April 6, 2023 | Categories: Core Faculty, Heart Regeneration, Research, Uncategorized | Tagged: ,

Researchers in the Murry Lab have demonstrated that a quadruple gene editing approach safely suppresses irregular heartbeats in stem cell therapy for injured hearts. Read More

A person with short, wavy hair wearing a red sweater stands smiling with arms crossed in a well-lit laboratory, surrounded by shelves with scientific equipment and supplies.

NIH Grant Advances Alzheimer’s Research – And Launches a Career

March 28, 2023 | Categories: Award, Core Faculty, Uncategorized | Tagged: , , ,

Tiara Schwarze-Taufiq, an ISCRM undergraduate fellow in 2021, is now a Research Scientist in the Young Lab thanks to an NIH R21 grant made possible in part by her own research. Read More

Diagram showing the activation of primary cardiac fibroblasts by TGFβ1, leading to activated fibroblasts. By day 4, fibroblasts are patterned and encapsulated; by day 11, indirect activation occurs via paracrine signaling.

ISCRM Researchers Recover Cells from Hydrogels with Minimal Disturbance

March 1, 2023 | Categories: Uncategorized

Research from the DeForest and Davis Labs describes a new method for cell extraction using engineered versions of an enzyme called sortase that have evolved to recognize and break specific peptide sequences. Read More

Five people stand around a table with drinks, laughing and holding tubing connected to containers, appearing to participate in a fun group activity in an indoor setting.

Science Nights at the Collective

February 21, 2023 | Categories: Uncategorized

Join ISCRM at the Collective in South Lake Union on the evening of May 4 for Cells in Jello: The Wonder of Biomaterials, a free public science talk. Read More

Fluorescent microscopy image of neurons showing glowing cell bodies and branching axons in green, magenta, and red against a dark background, highlighting neural structures and connections.

Ganglion cells created in mice in bid to fix diseased eyes

December 13, 2022 | Categories: Uncategorized

A UW Medicine team led by Tom Reh, PhD had previously shown that neurons could be coaxed from glial cells in the retinal tissue of mice. Now they’ve refined the process to produce specific cells. Read More