Meet the 2025 Tietze Award Winners

May 6, 2025 | Categories: Award, Core Faculty, Research, Uncategorized | Tagged: , ,

Smita Yadav and Nobuhiko (Nobu) Hamazaki have received prestigious awards from the John H. Tietze Foundation Trust that will help fuel promising research underway in their labs. Read More

User-Friendly 3D-Printed Device Will Allow Researchers to Model Human Tissue With Increased Control and Complexity

April 30, 2025 | Categories: Core Faculty, Research, Uncategorized | Tagged: , ,

The device known as STOMP, developed by researchers from the Sniadecki and Theberge Labs, is small enough to fit on a human fingertip and is compatible with existing tissue engineering technology. Read More

Reh Lab Shows Conclusively that AAV-delivered Genes Can Regenerate Mammalian Retinal Neurons

March 24, 2025 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

Researchers in the Reh Lab have produced the clearest evidence yet that AAV-delivered genes can stimulate regeneration in the mammalian retina Read More

Freedman Lab Tests a Promising mTOR Inhibitor in PKD Organoids

January 23, 2025 | Categories: Research | Tagged: , , ,

The study results suggest the molecule at the center of the study may be safer at higher doses and therefore more potent against harmful cysts. Read More

Yang Lab Co-Leads NIH-Funded Effort to Improve Genetic Testing for HCM

November 4, 2024 | Categories: Research | Tagged: , , ,

An NIH-funded partnership between ISCRM faculty member Dr. Daniel Yang and Dr. Lea Starita in the UW Department of Genome Sciences will use an innovative gene editing technology to sequence large numbers of variants of a mutation associated with hypertrophic cardiomyopathy. Read More

How Small Molecules Have a Big Impact on the Heart

October 23, 2024 | Categories: Core Faculty, Research | Tagged: , , ,

Researchers at UW and UCSD use a multiscale modeling tool show how small infusions of myosin can have a big impact on the whole heart. Read More

Modeling the Periodontal Ligament in 3D

October 22, 2024 | Categories: Core Faculty, Research | Tagged: ,

A new 3D modeling tool developed by the Sniadecki Lab and Dr. Tracy Popwics in the School of Dentistry could lead to regenerative therapies for periodontal diseases. Read More

New Gene Therapy for Muscular Dystrophy Offers Hope

July 17, 2024 | Categories: Core Faculty, Research | Tagged: , ,

A new gene therapy treatment for Duchenne muscular dystrophy (DMD) shows promise of not only arresting the decline of the muscles of those affected by this inherited genetic disease, but perhaps, in the future, repairing those muscles. Read More

Designed Proteins Guide Stem Cells to Form Blood Vessels

June 11, 2024 | Categories: Core Faculty, Research | Tagged: , ,

UW researchers have used computer-designed proteins to direct human stem cells to form new blood vessels in the lab, offering new hope for repairing damaged hearts, kidneys, and other organs. Read More

Why Tiny Changes in Protein Structure Can Lead to Big Problems for the Heart

May 2, 2024 | Categories: Research, Uncategorized | Tagged: , , ,

An NIH-funded collaboration involving ISCRM researchers has published a study describing how complementary areas of expertise produced new insights about hypertrophic cardiomyopathy at the protein, cell, and tissue levels. Read More