Helper or Culprit: Re-Examining the Role of Fibroblasts in Dilated Cardiomyopathy
September 11, 2025 | Categories: Core Faculty, Research, Uncategorized |In a paper published in Science, a multidisciplinary ISCRM research team of biologists, engineers, and physicians shows that fibroblasts, often thought of as helpers, may weaken the heart by causing a harmful cycle of stiffening and scarring. Read More
Key Upgrade to Protective Cell Delivery System Offers Greater Control with Light
August 27, 2025 | Categories: Core Faculty, Research |The DeForest Research Group unveils a new tool, known as PhoCoil, that protects injected cells as they travel to their destination and gives scientists greater control over them once they arrive. Read More
Meet the 2025 Tietze Award Winners
May 6, 2025 | Categories: Award, Core Faculty, Research, Uncategorized |Smita Yadav and Nobuhiko (Nobu) Hamazaki have received prestigious awards from the John H. Tietze Foundation Trust that will help fuel promising research underway in their labs. Read More
User-Friendly 3D-Printed Device Will Allow Researchers to Model Human Tissue With Increased Control and Complexity
April 30, 2025 | Categories: Core Faculty, Research, Uncategorized |The device known as STOMP, developed by researchers from the Sniadecki and Theberge Labs, is small enough to fit on a human fingertip and is compatible with existing tissue engineering technology. Read More
Reh Lab Shows Conclusively that AAV-delivered Genes Can Regenerate Mammalian Retinal Neurons
March 24, 2025 | Categories: Core Faculty, Research, Uncategorized |Researchers in the Reh Lab have produced the clearest evidence yet that AAV-delivered genes can stimulate regeneration in the mammalian retina Read More
Freedman Lab Tests a Promising mTOR Inhibitor in PKD Organoids
January 23, 2025 | Categories: Research |The study results suggest the molecule at the center of the study may be safer at higher doses and therefore more potent against harmful cysts. Read More
Yang Lab Co-Leads NIH-Funded Effort to Improve Genetic Testing for HCM
November 4, 2024 | Categories: Research |An NIH-funded partnership between ISCRM faculty member Dr. Daniel Yang and Dr. Lea Starita in the UW Department of Genome Sciences will use an innovative gene editing technology to sequence large numbers of variants of a mutation associated with hypertrophic cardiomyopathy. Read More
How Small Molecules Have a Big Impact on the Heart
October 23, 2024 | Categories: Core Faculty, Research |Researchers at UW and UCSD use a multiscale modeling tool show how small infusions of myosin can have a big impact on the whole heart. Read More
Modeling the Periodontal Ligament in 3D
October 22, 2024 | Categories: Core Faculty, Research |A new 3D modeling tool developed by the Sniadecki Lab and Dr. Tracy Popwics in the School of Dentistry could lead to regenerative therapies for periodontal diseases. Read More
New Gene Therapy for Muscular Dystrophy Offers Hope
July 17, 2024 | Categories: Core Faculty, Research |A new gene therapy treatment for Duchenne muscular dystrophy (DMD) shows promise of not only arresting the decline of the muscles of those affected by this inherited genetic disease, but perhaps, in the future, repairing those muscles. Read More