Gene Editing May Help Address Arrhythmia Challenges in Heart Regeneration

June 21, 2021 | Categories: Heart Regeneration, Research, Uncategorized | Tagged: , , ,

New data presented by ISCRM Director Chuck Murry suggests gene-editing may be the key to clearing a major hurdle for researchers hoping to remuscularize injured hearts with stem cell-derived cardiomyocytes Read More

Julie Mathieu

New Investigator Award for Julie Mathieu Funds Collaborative Cancer Research

June 11, 2021 | Categories: Award, Research | Tagged: , , , ,

Fueled in part by a New Investigator Award from the Cancer Consortium, ISCRM faculty member Julie Mathieu, PhD is partnering with scientists at the Institute for Protein Design and Fred Hutch to develop new treatments for renal cell carcinoma. Read More

Study Yields New Clue to Strokes of Undetermined Source

May 4, 2021 | Categories: Core Faculty, Research, Uncategorized | Tagged: , ,

Simulations shed light on heart-scarring similarities among patients with atrial fibrillation and those who had embolic stroke but no atrial fibrillation. Read More

Rainbow Heart

ISCRM Researchers Use Rainbow Reporters to Examine Proliferation of Engrafted Heart Cells

April 19, 2021 | Categories: Core Faculty, Heart Regeneration, Research, Uncategorized | Tagged: , , , ,

ISCRM investigators use rainbow cell technology to demonstrate that injected heart cells proliferate, a finding that could help researchers enhance the efficacy of cell therapy for heart disease and other conditions. Read More

Engineering Microvasculature in Full 3D Complexity

March 4, 2021 | Categories: Core Faculty, Research | Tagged: , , ,

ISCRM researchers led by Ying Zheng, PhD, detail a method to generate microvaculature in full 3D complexity using multiphoton ablation and laser-guided cellularization Read More

ISCRM Researchers Pursue Personalized Medicine for Heart Failure

December 3, 2020 | Categories: Award, Research | Tagged: , , , ,

With a Collaborative Science Award from the American Heart Association Jen Davis, Farid Moussavi-Harami , and Tom Daniel are on a mission to develop new tools to help cardiologists personalize treatments for certain heart diseases too. Read More

Stevens Lab Unveils Novel System for Regulating Gene Expression with Heat

September 30, 2020 | Categories: Research, Uncategorized | Tagged: , , , ,

Researchers hoping to create disease models or regenerate organs need systems that precisely mimic the degree of complexity found in the natural world. The Stevens Lab is helping to answer the call with a new system that regulates gene expression patterns using heat Read More

Zheng Lab Uses New 3D Model to Study Effect of Curvature on Endothelial Cells

September 16, 2020 | Categories: Research | Tagged: , , ,

Every day, million of cars navigate a complex network of wide, straight highways, busy streets and avenues, and side roads that bend and curve in unpredictable patterns. Now a new 3D modeling tool will help scientists study even more complex traffic patterns at work in our blood vessels. Read More