Study From Moltke Lab Describes How Immune Sentinel Tuft Cells Differentiate From Epithelial Stem Cells

May 12, 2023 | Categories: Core Faculty, Research | Tagged: ,

New research from the Moltke Lab at UW Medicine describes how our body generates an enigmatic cell type, known as tuft cells, that detects parasitic worms and helps to mobilize an immune response. Read More

SpyLigation Uses Light to Switch on Proteins

April 17, 2023 | Categories: Core Faculty, Research | Tagged: , , ,

Light-activation technology developed by the Cole DeForest Research Group has potential applications in tissue engineering, regenerative medicine, and understanding how the body works. Read More

Breaking Boundaries in Skin Research With Biosensors and Optogenetics

April 14, 2023 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

Cory Simpson, MD, PhD and Andre Berndt, PhD detail how advances in biosensor and optogenetic technology are opening up new possibilities in dermatology research. Read More

Gene-Edits Safely Reduce Irregular Heartbeats in Cell Therapy for Heart Disease

April 6, 2023 | Categories: Core Faculty, Heart Regeneration, Research, Uncategorized | Tagged: ,

Researchers in the Murry Lab have demonstrated that a quadruple gene editing approach safely suppresses irregular heartbeats in stem cell therapy for injured hearts. Read More

Research from Freedman Lab Reveals Surprising Finding About Common Cause of Kidney Disease

January 5, 2023 | Categories: Core Faculty, Research | Tagged: , ,

A paper from the Freedman Lab, published this week in Nature Communications, reveals a surprising finding about the way cysts form in PKD organoids, a discovery that could have clinical implications. Read More

ISCRM Researchers Identify Gene With Dual Influence on Bone and Muscle Development

November 29, 2022 | Categories: Core Faculty, Research | Tagged: , , , , ,

Using zebrafish as a model, researchers from the Musculoskeletal Systems Biology Lab describe how wnt16 dually influences bone and muscle development and growth. Read More

Cascadia Corridor Research Symposium Comes to Seattle

October 10, 2022 | Categories: Announcements, Core Faculty, Research | Tagged:

The symposium will take place November 3-4 on the UW Medicine South Lake Union campus and will feature keynote addresses from ISCRM Associate Director Jen Davis, PhD and David Granville, PhD, Professor and Associate Dean Research, Faculty of Medicine, University of British Columbia. Read More

MSBL Receives NIH Grant to Expand DEIA Mentorship

October 4, 2022 | Categories: Award, Core Faculty, Research | Tagged: , ,

The Musculoskeletal Systems Biology Lab (MSBL), directed by ISCRM faculty member Ron Kwon, has received a $431,765 award from the NIH in recognition of excellence in DEIA (diversity, equity, inclusion, and accessibility) mentorship. Read More

Xray image of a Zebrafish Fin

Exploring Regenerative Potential in Zebrafish and Humans

September 27, 2022 | Categories: Core Faculty, Research | Tagged: , , ,

A study from the Musculoskeletal Systems Biology Lab sheds a light on the characteristics of zebrafish cells that are able to differentiate from progenitor cells into bone cells, and then revert back to a progenitor state. Read More

Modeling a Muscle Disease in 3D

August 17, 2022 | Categories: Award, Core Faculty, Research, Uncategorized | Tagged: , ,

A team of investigators led by ISCRM faculty members David Mack, PhD and Nate Sniadecki, PhD have shown that is possible to recreate DMD with much more complexity in a 3D model of engineered heart tissue. Read More