Priming the Heart for Regeneration
January 10, 2022 | Categories: Research |In 2015, a team of inquisitive young scientists, absorbed in the study of metabolism, regeneration, and biological development, set out to answer a question. Could the way cells produce energy help explain why certain organisms have an envious ability to regenerate heart tissue after injury? And, if so, could that knowledge be used to help heal human hearts? Read More
ISCRM Research Sheds New Light on COVID-19 and Kidney Health
December 2, 2021 | Categories: Core Faculty, Research, Uncategorized |ISCRM researchers use kidney organoids to demonstrate that COVID-19 is capable of infecting kidney cells directly and test whether a synthetic protein designed by the Institute for Protein Design (IPD) might be capable of preventing infection. Read More
Nudging Cells to Repair Damaged Retinas
October 25, 2021 | Categories: Core Faculty, Research |Researchers led by ISCRM faculty member Tom Reh induce support cells in the retina to become neurons, an approach that someday could help restore vision. Read More
Watch a Brief Video About ISCRM
September 17, 2021 | Categories: Core Faculty, ResearchWatch this brief video about the collaborative research community harnessing advances in biology and engineering to confront the root causes of disease. Read More
Kelly Stevens, Jay Shendure, and Cole Trapnell Detail Spatial-Mapping Technology
July 2, 2021 | Categories: Core Faculty, Research |UW researchers have created a technique to build single-cell resolution spatial maps of the molecular profiles of mammal cell types Read More
Gene Editing May Help Address Arrhythmia Challenges in Heart Regeneration
June 21, 2021 | Categories: Heart Regeneration, Research, Uncategorized |New data presented by ISCRM Director Chuck Murry suggests gene-editing may be the key to clearing a major hurdle for researchers hoping to remuscularize injured hearts with stem cell-derived cardiomyocytes Read More
New Investigator Award for Julie Mathieu Funds Collaborative Cancer Research
June 11, 2021 | Categories: Award, Research |Fueled in part by a New Investigator Award from the Cancer Consortium, ISCRM faculty member Julie Mathieu, PhD is partnering with scientists at the Institute for Protein Design and Fred Hutch to develop new treatments for renal cell carcinoma. Read More
Study Yields New Clue to Strokes of Undetermined Source
May 4, 2021 | Categories: Core Faculty, Research, Uncategorized |Simulations shed light on heart-scarring similarities among patients with atrial fibrillation and those who had embolic stroke but no atrial fibrillation. Read More
ISCRM Researchers Use Rainbow Reporters to Examine Proliferation of Engrafted Heart Cells
April 19, 2021 | Categories: Core Faculty, Heart Regeneration, Research, Uncategorized |ISCRM investigators use rainbow cell technology to demonstrate that injected heart cells proliferate, a finding that could help researchers enhance the efficacy of cell therapy for heart disease and other conditions. Read More
Engineering Microvasculature in Full 3D Complexity
March 4, 2021 | Categories: Core Faculty, Research |ISCRM researchers led by Ying Zheng, PhD, detail a method to generate microvaculature in full 3D complexity using multiphoton ablation and laser-guided cellularization Read More